Cao et al. [5] observed that miR-335 expression was reduced in epithelial ovarian cancer tissue samples, especially in omental metastases, and low miR-335 levels emerged as an independent prognostic factor for poor overall and relapse-free survival; Wang et al. [32] also identified miR-335 as a tumor suppressor by targeting the ROCK1 gene and inhibiting osteosarcoma cell migration and invasion. Here, ROCK1 is linked to neoplasm.