COL4A1 and cataract: Eyes of both ActbCre;Col4a1+/Flex41 and Col4a1+/Δex41 mice exhibited various ocular defects that were never observed in littermate controls (Col4a1+/Flex41 and ActbCre), including cataracts, iridocorneal adhesions, compressed or absent trabecular meshwork and Schlemm's canals, and dysgenic ciliary bodies (compare K,L with I,J, and O,P with M,N in Fig. 1).