In accordance with these observations, we found increased expression of the gene encoding FasL in SALS2 patients and SOD1G93A mice on day 70, before the development of motor impairment, suggesting a role of FasL as a possible target for treating ALS in the early stage of the disease (Figs. 3b and 5). The gene discussed is FASLG; the disease is amyotrophic lateral sclerosis.