IL10 and amyotrophic lateral sclerosis: To this regard, it is interesting to note that glatiramer acetate, besides its activity as MHC modulator (discussed above), exerts its anti-inflammatory effects also by inducing T helper cells to secrete IL-10 and other anti-inflammatory cytokines, providing a multi-targeted mechanism of action for the treatment of ALS (Arnon and Aharoni 2004; Vieira et al. 2003).