Most of the genes from day 1 appeared 2-fold downregulated (e.g., CDCA7L or GBP2), but three were 3–5-fold upregulated (C11orf96, GLUL, TM4SF19) relative to H0 (Table 3) when developing a HARS without pancytopenia. This evidence concerns the gene GBP2 and Pancytopenia.