Interestingly MAP6 also interacts with TMEM106B, a major risk factor of frontotemporal dementia (FTD) and a modifier of C9orf72-associated ALS and FTD that is involved in axonal transport of lysosomes (Schwenk et al., 2014, van Blitterswijk et al., 2014, Gallagher et al., 2014, Van Deerlin et al., 2010). The gene discussed is MAP6; the disease is frontotemporal dementia.