No changes in chymotrypsin-like proteasome activity could be observed at the time of lorazepam injection, 40 min after intra-amygdala KA injection when analyzing all three hippocampal subfields (Additional file 1: Figure S2C); however, a small decrease in chymotrypsin-like proteasome activity was evident 4 h post status epilepticus in the CA1 subfield of the hippocampus (Fig. 2c). The gene discussed is CTRL; the disease is status epilepticus.