Using the Fisher's Exact Probability test, the genetic differentiation of SNP alleles and SNP genotype results revealed significant differences in SNP allele frequencies for the CTNS, IGF2R, GHR (Polish HF breed), IGF2BP3, GHR (Hereford breed) and IQGAP2 SNP loci (S58 Table). The gene discussed is IGF2R; the disease is hydrops fetalis.