CD4 and colitis: In addition, because a CD62LlowCD44high phenotype has been reported for colitogenic CD4+ memory T cells in murine colitis models [22], aiTregs that are reprogrammed as Th2-type cells might be retained as a pathogenic memory T-cell subset in the MLNs or other tissues of EW-fed OVA23-3 and R23-3 mice.