CD4 and Abnormal intestine morphology: In our OVA23-3 system, the enteropathy observed in EW-fed OVA23-3 mice is not dependent on IgE responses, but on excessive IL-4 production by OVA-specific CD4+ T cells [7]; therefore, in the OVA23-3 model of T-cell-dependent food allergic enteropathy, aiTregs may influence both the aggravation of and recovery from the food-induced inflammation.