We previously showed that female CD200R-/- BALB/c mice could be cured from EMT6 breast cancer by immunization with irradiated EMT6 cells and CpG after surgical resection of the primary tumor [4], with no metastases (macroscopic lung nodules or microscopic nodules detected by limiting dilution analysis of DLN) apparent >300days post surgery. The gene discussed is CD200R1; the disease is breast carcinoma.