IFIH1 and systemic lupus erythematosus: In addition to the two genetic variants associated with IL-6 and IP-10 in the current study, SNP rs13023380 has recently been associated with the CARD1/CARD2 encoding region of IFIH1 in SLE patients [4] and lies closest to the IL-6 and IP-10 associated SNPs in our IFIH1 LD map.