We observed that those subjects with the minor allele for rs76162067 tended to have higher levels of IL-6, while those with the minor allele for rs79711023 tended to have lower levels of IP-10, including both SLE patients and FDRs of SLE patients, who are at increased risk of transitioning to classified disease [6, 25]. The gene discussed is CXCL10; the disease is systemic lupus erythematosus.