Along those lines, investigations into prenatal exposures of infants with MLL-r leukemia have suggested that bioflavonoids found in foods and herbal remedies such as dipyrone (“Mexican aspirin”); senna in herbal teas; quercetin, a bioflavonoid found in onions, red wine, and other foods; and genistein found in soybean products could act as inhibitors of topoisomerase II (100, 120, 121) and promote rearrangement of the MLL locus in a variety of cells, including CD34+ hematopoietic progenitor cells (120, 122). Here, KMT2A is linked to leukemia.