ITIH5 and breast carcinoma: Upon stable transfection using a full-length ITIH5 cDNA pBK-CMV expression vector (ΔpBK-ITIH5 clones, also referred to as ITIH5) or the empty vector alone (ΔpBK-mock clones, also referred to as mock), single-cell clones were generated based on well-differentiated, luminal T47D tumor cells (Fig. 2a) and on the metastatic, basal-type MDA-MB-231 breast cancer cell line (Fig. 2b).