Findings from the cross-sectional analysis performed in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort showed that evidence of significant linear trends for increasing trends in biomarkers of arteriosclerosis with graded increases in GGT, including oxidized low-density lipoproteins (oxLDL), interleukin-6 (IL-6), C-reactive protein (CRP), and soluble intercellular adhesion molecule-1 (sICAM-1)[56]. This evidence concerns the gene ICAM1 and arteriosclerosis disorder.