Regardless of the molecular subgroup of the primary tumor, all six patient-derived medulloblastoma cell lines exhibited a uniform phenotype: immunofluorescence showed the nuclear localization of YAP1 accompanied by strong cytoplasmic positivity for β-catenin and filamin A, as well as weak positivity for GAB1 (Table 4, Fig 2). This evidence concerns the gene YAP1 and medulloblastoma.