Some have reported increased Dicer expression in prostate adenocarcinoma cancer29 and Burkitt's lymphoma.30 In contrast, others have reported reduced Dicer expression in nasopharyngeal carcinoma31 and gastric cancer.32 In the present study, Dicer expression in CCA cells was significantly higher than that in the HIBEpic cells. The gene discussed is DICER1; the disease is cholangiocarcinoma.