As a biological treatment for autoimmunity, MSC appear to be an ideal cellular population owing to the following properties: they express CXCR4 and several other chemokine receptors, allowing their migration to areas of tissue injury, thereby permitting intravenous administration, and they secrete growth factors such as IGF-1, HGF-1, bFGF, allowing MSC to induce an indirect healing function23. This evidence concerns the gene IGF1 and Autoimmunity.