Cytokines like granulocyte–macrophage‐derived soluble factor (GM‐CSF) and vascular endothelial growth cell factor (VEGF), which promote myelopoiesis toward MDSCs, are factors secreted by tumor cells (Ostrand‐Rosenberg & Sinha, 2009; Youn & Gabrilovich, 2010; Gabrilovich et al., 2012; Talmadge & Gabrilovich, 2013). The gene discussed is CSF2; the disease is neoplasm.