Heterozygous ADCY5 mutations, encoding adenylyl cyclase 5, cause familial dyskinesia with facial myokymia (FDFM; OMIM:606703) and benign hereditary chorea (BHC; OMIM:118700), comprising ‘ADCY5-related dyskinesia’ [1–5]. This evidence concerns the gene ADCY5 and Benign familial chorea.