CA7 and colorectal carcinoma: For example, we were the first to report that carbonic anhydrase VII (CA7) expression plays an initiating but not progressive role in CRC (Chu et al., 2014b) Subsequently, two studies (Kalmár et al., 2015; Yang et al., 2015) verified the role of CA7 by western blot and immunohistochemistry analyses as well as qRT-PCR analyses of clinical samples including colorectal paraffin-embedded (FFPE) tissue.