KIR3DL1 and acute myeloid leukemia: Cooley et al. (50, 64, 65) systematically investigated the influence of the KIR haplotype B. In summary, a high number of KIR haplotype B defining receptors, especially of those coded in the centromeric regions, showed beneficial effects on survival of HLA C1/x AML recipients after ATG-free HSCT without increased GVHD and without benefit of KIR-ligand mismatch.