Radicke and colleagues analyzed the functional effects of KChIP2 and KCNE subunits on Kv4.3L and also discovered HF-associated remodeling of Kv4.3 splicing and β subunits, but did not examine functional effects on Kv4.3S (Radicke et al., 2006). This evidence concerns the gene KCNIP2 and hydrops fetalis.