Furthermore, it was also found that MCP-1 and NF-κB expression levels were positively correlated with IL-10 levels in the peripheral blood of animals with tuberculosis, and with the percentage of CD4+ CD25+ Foxp3+ Tregs subsets accounting for CD4+ lymphocyte, while both of the expressions were negatively correlated with IFN-γ, IL-2 and the percentage of CD4+ T lymphocyte. The gene discussed is IFNG; the disease is tuberculosis.