ACHE and early-onset autosomal dominant Alzheimer disease: Accordingly, patients with Alzheimer disease exhibit significant decreases in power in the delta and theta bands during treatment with rivastigmine, which is an acetylcholinesterase inhibitor, indicating that there is a shift of the power spectrum toward normalization.[37] In the future, it will be necessary to determine the relationships of the neurophysiological changes in IGD patients after treatment with changes in cognitive function.