RHEBP1 and allergic asthma: To assess the role of Rheb1 in allergic asthma, we first generated mice with a Rheb1 specific knockout by mating floxed Rheb1 mice with Lys-MCre mice (which express a Cre recombinase under the direction of the Lys-M promoter) (as shown in Fig. 2a, Lys-MCre-Rheb1flox/flox mice are referred to as homozygote KO mice and Rheb1flox/flox as WT mice).