In the RGD-TRAIL-ELP group, a greater amount of fluorescence was enriched in the tumor, which was 2.5-fold higher than that in the RGD-TRAIL group; other tissues, such as heart, liver, spleen, lung and kidney, presented relatively weaker intensity, which further confirmed the tumor oriented accumulation of RGD-TRAIL-ELP. The gene discussed is TNFSF10; the disease is neoplasm.