CD4+ NKG2D+ T cells are associated with inflammatory diseases, such as rheumatoid arthritis (RA) 5, 6, granulomatosis with polyangiitis 7, Crohn's disease 8, 9, 10, multiple sclerosis 11 and infection by human cytomegalovirus (CMV) 12. The gene discussed is CD4; the disease is rheumatoid arthritis.