Breast cancer is a significant health concern in humans and small animals, especially in Siamese cat, so special emphasis was given to ascertain cancer associated sequence variants of heat shock protein-beta1 (Hspb1) gene in this neoplasm (Rutteman and Misdorp, 1992 ▶; Zappulli et al., 2005 ▶). Here, HSPB1 is linked to breast cancer.