Moreover, IgG3 RIs were directly correlated to the number of recent malaria episodes (p = 0.003; r = 0.315; Figure S1A in Supplementary Material) and inversely associated with the time elapsed from the last malaria episode (p = 0.031; r = −0.258; Figure S1B in Supplementary Material). The gene discussed is IGHG3; the disease is malaria.