We also evaluated the effect of alcohol exposure during adolescence on the gene expression of neuropeptides linked to anxiety/stress responses and their receptors [neuropeptides: corticotropin-releasing factor (CRF) (Crh) and neuropeptides Y (NPY) (Npy); and receptors: CRF1R (Crhr1), CRF2R (Crhr2), NPY1R (Npy1r), NPY2R (Npy2r) and NPY5R (Npy5r)]. The gene discussed is CRHR2; the disease is Anxiety.