PRLR and melanoma: However, we observed that the RNA levels of PRLR in these melanoma cells are more than 100-fold lower than the GHR RNA levels, and we observed no significant variation due to altered autocrine PRL-PRLR level on GHRKD induced effects in either the phosphorylation levels of intracellular signaling intermediates or in the tumoral phenotypes of migration, invasion and proliferation.