Based on the cut-off value at >twofold change and the p value at <0.01, we investigated that 6 miRNAs were differentially expressed both in LTNPs and CPs, miR-342-5p (↓), miR-212-3p (↑), miR-494-3p (↑), miR-939-5p (↑), miR-1225-5p (↑), an miR-513a-5p (↑) in LTNPs and CPs, compared with UCs, indicating these deregulated miRNAs may be HIV-1-specific miRNAs of CD4+ T cells following HIV-1 infection. Here, CD4 is linked to HIV-1 infection.