Among the 28 inflammatory molecules examined, 12 were significantly overexpressed (p < 0.05) in OCB+ compared to both controls and OCB− MS patients (Fig. 2b, c): IL6, IL8, IL10, CXCL13, CXCL12, TNF, APRIL, BAFF, IFNγ, MMP2, osteopontin (OPN), sCD163. This evidence concerns the gene TNF and myeloid sarcoma.