Following infection, Mφ derived from WT mice exhibited a higher mRNA level of IL-1β 48 and 72 h post infection, while the IL-1β mRNA level from the TLR2/9−/− mice showed a slight increase with a peak at 48 h of infection; however, this level was lower than that in the WT mice and was followed by a decrease at the next time point. This evidence concerns the gene IL1B and infection.