LLC cells (106 cells) were transplanted i.m. into the right thigh muscle of C57Bl/6J mice and, starting from the fourth day (the beginning of the exponential growth of the tumour and metastasis [34]), mice received i.m. saline buffer (control) or DNase I (0.12 mg /kg) for 2 weeks. The gene discussed is DNASE1; the disease is neoplasm.