Because of the especially low incidence of SRSF2 mutations in Chinese MDS cases (3.4% vs. 13–15% in foreign literature)7, 8, 20, the cooperative relationship between the mutations in SRSF2 and STAG2/RUNX1/ASXL1/IDH2 confirmed in the published literature was not validated by our results7, 8. This evidence concerns the gene IDH2 and myelodysplastic syndrome.