MAPT and supranuclear palsy, progressive, 1: In their study, Marquié et al. [111] compared the regional in vivo ante-mortem binding of [18F]AV-1451, its post-mortem binding on autoradiography, and tau immunostaining in three cases with 4R tau aggregates: two patients with pathologically confirmed PSP, and one patient with a MAPT mutation (P301L) presenting with an unusual histopathological phenotype of abundant cortical and white matter small grain-like tau inclusions instead of the expected NFTs and neuritic processes.