High tau deposition (measured with [18F]AV-1451, [18F]THK5317 or [18F]THK5351 PET) was observed in patients with a clinical diagnosis of PSP, in areas expected based on the neuropathological literature: the basal ganglia, thalamus, dentate nucleus of the cerebellum, and midbrain [36, 53, 87–89]. This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.