AURKA and cancer: Human Aurora kinase A (AURKA) is essential for centrosome duplication, maturation and separation.6 AURKA is a potent oncogene that has the capacity to transform certain cell lines when overexpressed.7 Recent evidence demonstrated that AURKA could regulate c-Myc expression through cooperating with hnRNP K.8 AURKA overexpression is also a hallmark of many cancers and can enhance chromosomal instability through centrosome amplification.