AURKA and gastric cancer: A previous study showed that AURKA overexpression and amplification are involved in differentiated-type gastric carcinogenesis and the development of aneuploidy, suggesting that it might contribute to the initiation and progression of gastric cancer.9 AURKA has also been implicated in taxane and microtubule destabilizing drug resistance;10 however, its role in gastric cancer, especially in resistance to DNA-damaging therapeutic agents remains undefined.