Patients with a heterozygous (or homozygous) mutation in the GBA1 gene, especially c.1226A>G (N370S), but also c.1448T>C (L444P), c.84dup, c.115+1G>A (IVS2+1G>A), c.1297G>T (V394L), and c.1604G>A (R496H), are now considered at risk for Parkinson’s disease (PD) [40,41,42]. The gene discussed is GBA1; the disease is Parkinson disease.