Consistent with higher neutrophil fungicidal functions, gal3−/− mice had better survival (Figure 7A) and lower fungal burdens in kidneys and brain (Figure 7B) than gal3+/+ mice when systemically infected with Candida. While gal3+/+ mice sustained multiple abscesses in the kidney with their kidney weights being about 2.3-fold of that of uninfected mice, gal3−/− mice exhibited only minimal gross renal pathology and relatively less change in kidney weights (Figure 7C). The gene discussed is LGALS3; the disease is abscess.