A common mechanism associated with allergy triggered by biocontrol agents such as B. bassiana (Westwood et al., 2005, 2006), Metarhizium anisopliae (Ward et al., 2011), Paecilomyces and Trichoderma viride (Beezhold et al., 2008), and Penicillium oxalicum (Kochar et al., 2014) is the production of IgE against fungal molecules observed in animal models and human patients. Here, IGHE is linked to allergic disease.