PITX1 and breast cancer: The expression of Caspase-3 was 45% and 55% in the ADLT and ADHT groups, respectively, which were also statistically significant as compared with that found in the BC group (16.67%; P = 0.0001 and P = 0.0001, respectively); this observation suggested that BFT-2 could inhibit the proliferation of cells and promote apoptosis.