However, silencing of SOD3 in PTC MSCs (PTC MSC SOD3 RNAi) failed to show increased cancer cell migration (Fig. 6C), indicating that SOD3 might have a different function in fibrotic MSCs or that the activation process of PTC MSCs modifies the ROS balance, hence altering the effect of single redox genes. This evidence concerns the gene SOD3 and cancer.