POU5F1 and Parkinson disease: We therefore examined the expression of the pluripotent genes NANOG, OCT4, SSEA4, and TRA-1-81, and the neural crest genes p75NTR and SOX10. HaNCSCs were isolated from age-matched controls, individuals with heterozygous GBA1 (N370S/WT) mutations, and sporadic PD patients (for details see Table S1).