NF1 and neoplasm: In addition to the NF1 andSUZ12 genes, patients with NF1 microdeletions are also hemizygous for three othergenes with putative tumour suppressor function: ATAD5 and the microRNA genes MIR193A and MIR365B. Whilst theimportance of SUZ12 loss in MPNST progressionhas now been well documented, rather less is known about the co-deleted genesATAD5, MIR193A, MIR365B and theirinvolvement in MPNST pathogenesis.