Several studies havesuggested that intellectual disability occurs disproportionately more frequentlyin NF1 microdeletion patients than in thegeneral NF1 population (Kayes et al. 1994; Rasmussen et al. 1998; Korf et al. 1999; Venturin et al. 2004b; reviewed by Mensink et al. 2006). This evidence concerns the gene NF1 and Intellectual disability.