Although such comparative analyses have beenattempted to assess differences in height (Ning et al. 2016), cognitive capability (Descheemaeker et al.2004) or the frequency ofcardiovascular anomalies (Nguyen et al. 2013), they have not as yet been performed methodically in thecontext of the number of neurofibromas and other NF1 microdeletion-associated clinical features. Here, NF1 is linked to plexiform neurofibroma.