The MIR365B gene, locatedwithin the NF1 microdeletion region(Fig. 1), also encodes an miRNA withknown tumour suppressor function, as evidenced by its ability to target specifictranscription factors, such as NKX2-1 and TTF1, in non-small cell lung cancer(Qi et al. 2012; Kang et al.2013; Sun et al. 2015). This evidence concerns the gene NF1 and neoplasm.