We also integrated the DMR results of ABBA with transcription factor binding site analysis, RNA-seq and ChIP-seq data generated in the same system, and, in this, we revealed a previously unappreciated role for the Ifitm3 gene in the pathogenesis of glomerulonephritis, providing a proof-of-concept for real data applications of the ABBA approach. Here, IFITM3 is linked to glomerulonephritis.