In the early stage of schistosome infection of mice, the IFN-γ level in the sera was significantly higher than that in the rSj CP1412 immunization/infection (t(4) = 18.49, P < 0.0001) and healthy groups (t(4) = 34.35, P < 0.0001) on day 21 post-infection (Fig. 10a). The gene discussed is IFNG; the disease is infection.