As the rSj CP1412 immunization of mice could inhibit inflammation in the early stage of schistosome infection, the serum IFN-γ level of the rSj CP1412 immunization/infection group was significantly lower than that of the infection group (P < 0.05) (Fig. 10a), and the IL-4 secretion from mouse splenic cells increased. The gene discussed is IFNG; the disease is infection.