The lncRNA UCA1 can bind to BRG1, the core subunit of the SWI/SNF complexes, and damage the remodeling activity of BRG1, which reduces the expression of p21 by blocking BRG1 binding to the p21 promoter and promotes the proliferation of bladder cancer cells [35]. This evidence concerns the gene SMARCA4 and urinary bladder carcinoma.