These analyses revealed that there was no difference in the expression of matrix metalloprotease 2 (MMP2), matrix metalloprotease 9 (MMP9), vascular endothelial growth factor (VEGF), CXCL2 or fibroblast growth factor (FGF) in melanoma-carrying WT vs. multiple KO animals (Figure 3). Here, MMP9 is linked to melanoma.