ASCL1 and non-small cell lung carcinoma: This included downregulation of miR-200 family members (important regulators of EMT, metastasis, and disease recurrence in NSCLC) [28, 38]; higher ZEB1/2, FOXO1, and NEUROD1; and decreased levels of stem cell markers (e.g., ALDH1A1) and other SCLC drivers (e.g., MYCL1, ASCL1) [32, 39].