We treated primary myometrial and leiomyoma cells with strawberry extract at 250 μg/ml for 48 h alone or activin A (4 nM) alone or combination of strawberry and activin A. We found that strawberry extract significantly reduced activin A induced fibronectin, collagen1A1, and versican mRNA expression in leiomyoma cells (Figure 5). The gene discussed is VCAN; the disease is leiomyoma.