SERPINE1 and leiomyoma: To evaluate PAI-1 expression we treated myometrial and leiomyoma cells with activin A (4 nM) for 2 h in 48 h pre-treated with strawberry extract (250 μg/ml) or strawberry extract (250 μg/ml) alone for 48 h or activin A (4 nM) alone for 2 h.